Q-actin  —already clinically validated for joint health—may offer additional benefits for healthy aging. Its ability to modulate inflammatory markers like tumor necrosis factor-alpha (TNF-α) positions Q-actin as a multifunctional ingredient with broad potential.

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A randomized, double-blind, placebo-controlled clinical trial found that
Q-actin can improve sleep quality and may help support cognitive performance in healthy older adults.

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Study Design

In the 12-week study, 47 adults ages 50 to 78 received either two Q-actin gummies (20 mg/day) or a matched placebo. Participants were not pre-selected for sleep or cognitive issues and were instructed to maintain their usual diet and activity levels throughout the study.

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Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI). Neuromuscular function was measured via the Nine-Hole Peg Test, and urinary levels of melatonin and its metabolites were assessed as biological markers of sleep regulation.

 

Key Findings

• Significant increases in melatonin, 6-sulfatoxymelatonin, and
  6-hydroxymelatonin

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• Improved subjective sleep quality based on PSQI scores

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• Notable gains in finger dexterity, indicating enhanced
  neuromuscular coordination

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• No serious adverse events and >99% compliance rate

 

Researchers noted that improved finger dexterity may reflect better neuromuscular function, which is closely tied to cognitive performance in aging adults.

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The results were published in Frontiers in Nutrition, May 2025.​​​​​​

 

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